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Featured Analytical Instrument
FTA-064 Amphetamine and Methamphetamine in Urine Analyzer
Determination of Amphetamine and Methamphetamine in Urine - Methamphetamine is metabolized mainly to amphetamine, which is then metabolized to minor metabolites including 4-hydroxyamphetamine, 4-hydroxynorephedrine and norephedrine. Conversion to the metabolites is strongly influenced by the pH of the urine; in alkaline urine, the conversion of the parent compounds occurs to a much greater extent than in acidic urine.
Abuse of the amphetamines is confirmed by monitoring the parent drugs in urine. The amphetamines are simple molecules that are closely related to substances found in over-the-counter and legal prescription medications. After the normed preparation the sample is injected in a GC/TOF system.